2021

31.

Ito Y, Fukuda M, Matsuzawa H, Masuda H, Kobayashi Y, Hasegawa N, Kitaura H, Kakita A, Fujii Y (2021) Deep learning-based diagnosis of temporal lobe epilepsy associated with hippocampal sclerosis: an MRI study. Epilepsy Res 178: 106815

30.

Natsumeda M, Igarashi H, Gabdulkhaev R, Takahashi H, Motohashi K, Ogura R, Watanabe J, Tsukamoto Y, Okamoto K, Kakita A, Nakada T, Fujii Y (2021) Detection of 2-hydroxyglutarate by 3.0-tesla magnetic resonance spectroscopy in gliomas with rare IDH mutations: making sense of “false-positive” cases. Diagnostics 11 (11): 2129

29.

Kimura A, Kato S, Takekoshi A, Yoshikura N, Yanagida N, Kitaguchi H, Kakita A, Shimohata T (2021) Autoimmune GFAP astrocytopathy diagnosed as isolated central nervous system lymphomatoid granulomatosis. J Neuroimmunol 361: 577748

28.

Koike Y, Sugai K, Hara N, Ito J, Yokoseki A, Ishihara T, Yamagishi T, Tsuboguchi S, Tada M, Ikeuchi T, Kakita A, Onodera O (2021) Age-related demethylation of the TDP-43 autoregulatory region in the human motor cortex. Commun Biol 4 (1): 1107

27.

Kato T, Manabe R, Igarashi H, Kametani F, Hirokawa S, Sekine Y, Fujita N, Saito S, Kawashima Y, Hatano Y, Ando S, Nozaki H, Sugai A, Uemura M, Fukunaga M, Sato T, Koyama A, Saito R, Sugie A, Toyoshima Y, Kawata H, Murayama S, Matsumoto M, Kakita A, Hasegawa M, Ihara M, Kanazawa M, Nishizawa M, Tsuji S, Onodera O (2021) Candesartan prevents the progression of arteriopathy in CARASIL model mice. J Clin Invest 131 (22): e140555

26.

Toyoshima Y, Takahashi H, Katada S, Kojima N, Tada M, Nani T, Koike R, Nozawa T, Aida I, Nakajima T, Onodera O, Kakita A (2021)
Parkinson’s disease and parkinsonism: clinicopathologic discrepancies on diagnosis in three patients. Neuropathology 41 (6): 450-456

25.

Shi Y, Zhang W, Yang Y, Murzin A, Falcon B, Kotecha A, van Beers M, Tarutani A, Kametani F, Garringer HJ, Vidal R, Hallinan GI, Lashley T, Saito Y, Murayama S, Yoshida M, Tanaka H, Kakita A, Ikeuchi T, Mann DMA, Kovacs GG, Revesz T, Ghetti B, Hasegawa M, Goedert M, Sheres SHW (2021) Structure-based classification of tauopathies. Nature 598 (7880): 359-363

24.

Kitaura H, Itoh Y, Hiraishi T, Fujii Y, Fukuda M, Kakita A (2021) Reactive astrocytes contribute to epileptogenesis in patients with cavernous angioma. Epilepsy Res 176: 106732

23.

Yoshitomi S, Hamano SI, Hayashi M, Sakuma H, Hirose S, Ishii A, Honda R, Ikeda A, Imai K, Jin K, Kada A, Kakita A, Kato M, Kawai K, Kawakami T, Kobayashi K, Matsuishi T, Matuo T, Nabatame S, Okamoto N, Ito S, Okumura A, Saito A, Shiraishi H, Shirozu H, Saito T, Sugano H, Takahashi Y, Yamamoto H, Fukuyama T, Kuki I, Inoue Y, Japan Rare Epilepsy Syndrome Resistry Group JRESG (2021) Current medico-psycho-social conditions of patients with West syndrome in Japan. Epileptic Disord  23 (4): 579-589

22.

Kunii Y, Matsumoto J, Izumi R, Nagaoka A, Hino M, Akatsu H, Hashizume Y, Kakita A, Yabe H (2021) Evidence for altered phosphoinositide signaling-associated molecules in the postmortem prefrontal cortex of patients with schizophrenia. Int J Mol Sci 22 (15): 8280

21.

Sasahara T, Satomura K, Tada M, Kakita A, Hoshi M (2021) Alzheimer’s Aβ assembly binds sodium pump and blocks endothelial NOS activity vis ROS-PKC pathway. iScience 24 (9): 102936

20.

Natsumeda M, Kanemaru Y, Kawaguchi Y, Umezu H, Kakita A, Fujii Y (2021) Less-invasive diagnosis of disseminated epithelioid glioblastoma harboring BRAF V600E mutation by cerebrospinal fluid analysis – a case report. Clin Case Rep 9 (7): e04551

19.

北浦弘樹、柿田明美 (2021) 海馬硬化症のてんかん原性. Epilepsy 15 (2): 74-77

18.

Sugita Y, Takahashi K, Fukuda K, Kimura Y, Furuta  T, Arakawa F, Ohshima K, Nakamura H, Miyata H, Watanabe M, Kakita A (2021) Primary non-dural central nervous system marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue type mimicking CNS inflammatory diseases. J Neuropathol Exp Neurol 80 (8): 789-799

17.

Natsumeda M, Chang M, Gabdulkhaev R, Takahashi H, Tsukamoto Y, Kanemaru Y, Okada M, Oishi M, Okamoto K, Rodriguez FJ, Kakita A, Fujii Y, Schreck KC (2021) Predicting BRAF V600E mutation in glioblastoma-utility of radiographic features. Brain Tumor Pathol 38 (3): 228-233

16.

Mori F, Miki Y, Tanji K, Kon T, Tomiyama M, Kakita A, Wakabayashi K (2021) Role of VAPB and vesicular profiles in α-synuclein aggregates in multiple system atrophy. Brain Pathol 31 (6): e13001

15.

Miura T, Iwasaki T, Mezaki N, Sato T, Saito S, Saito R, Ajioka Y, Kakita A, Mashima T (2021) Long spinal cord lesion caused by venous congestive myelopathy associated with intravascular large B-cell lymphoma. Intern Med 60 (23): 3809-3816

14.

Sainouchi M, Tanaka H, Shimizu H, Mashima T, Fukushima T, Ishihara T, Makino K, Onodera O, Kakita A (2021) Hemiplegic type ALS: clinicopathological features of two autopsied patients. J Neurol Neurosurg Psychiatry 92 (9): 1014-1016

13.

Seike N, Yokoseki A, Takeuchi R, Saito K, Miyahara H, Miyashita A, Ikeda T, Aida I, Nakajima T, Kanazawa M, Wakabayashi M, Toyoshima Y, Takahashi H, Matumoro R, Toda T, Onodera O, Ishikawa A, Ikeuchi T, Kakita A (2021) Genetic variations and neuropathologic features of patients with PARK2. Mov Disord 36 (7): 1634-1643

12.

Li J, Wisessmith W, Ito J, Kakita A, Kunisawa K, Shimizu T, Ikenaka K (2021) Exploring the factors underlying remyelination arrest by studying the post-transcriptional regulatory mechanisms of Cystatin F gene. J Neurochem 157 (6): 2070-2090

11.

Zhang L, Toyoshima Y, Takeshima A, Shimizu H, Tomita I, Onocera O, Takahashi H, Kakita A (2021) Progressive supranuclear palsy: neuropathology of patients with short disease duration due to unexpected death. Neuropathology 41 (3): 174-182

10.

豊島靖子、岡本浩一郎、小野寺理、柿田明美 (2021) 中毒・代謝障害の白質脳症の画像と病理.Annual Review 神経2021.鈴木則宏,荒木信夫,宇川義一,桑原聡,塩川芳昭(編集).中外医学社 pp. 21-29 (total 376 pages)

9.

Sainouchi M, Hatano Y, Tada M, Ishihara T, Ando S, Kato T, Tokunaga J, Ito G, Miyahara H, Toyoshima Y, Yokoseki A, Ozawa T, Akazawa K, Onodera O, Kakita A (2021) A novel splicing variant of ANXA11 in a patient with amyotrophic lateral sclerosis: histologic and biochemical features. Acta Neuropathol Commun 9 (1): 106

8.

Matsui H, Ito J, Matsui N, Uechi T, Onodera O, Kakita A (2021) Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson’s disease. Nat Commun 12 (1): 3101

7.

Yoshihara S, Jiang X, Morikawa M, Ogawa T, Ichinose S, Yabe H, Kakita A, Toyoshima M, Kunii Y, Yoshikawa T, Tanaka Y, Hirokawa N (2021) Betaine ameliorates schizophrenic traits by functionally compensating KIF3-based CRMP2 transport. Cell Rep 35 (2): 108971

6.

Miyahara H, Natsumeda M, Kanemura Y, Yamazaki K, Riku Y, Akagi A, Oohashi W, Shofuda T, Yoshioka E, Sato Y, Taga T, Naruke Y, Hasegawa D, Yoshida M, Sakaida T, Okada N, Watanabe H, Ozeki M, Arakawa Y, Yoshimura J, Fujii Y, Suenobu S, Ihara K, Hara J, Kakita A, Yoshida M, Iwasaki Y (2021) Topoisomerase IIβ immunoreactivity (IR) co-localizes with neuronal marker-IR but not glial fibrillary acidic protein-IR in Gli3-positive medulloblastomas: an immunohistochemical analysis of 124 medulloblastomas from the Japan Children’s Cancer Group. Brain Tumor Pathol 38 (2): 109-121

5.

On J, Natsumeda M, Watanabe J, Saito S, Kanemaru Y, Abe H, Tsukamoto Y, Okada M, Oishi M, Yoshimura J, Kakita A, Fujii Y (2021) Low detection rate of H3K27M mutations in cerebrospinal fluid taken by lumbar punctute in newly diagnosed diffuse midline gliomas. Diagnostics 11 (4): 681

4.

Izumi R, Hino M, Wada A, Nagaoka A, Kawamura T, Mori T, Sainouchi M, Kakita A, Kasai K, Kunii Y, Yabe H (2021) Detailed postmortem profiling of inflammatory mediators expression revealed dpost-inflammatory alteration in the superior temporal gyrus of schizophrenia. Front Psychiatry 12: 653821

3.

Natsumeda M, Miyahara H, Yoshimura J, Nakata S, Nozawa T, Ito J, Kanemaru Y, Watanabe J, Tsukamoto Y, Okada M, Oishi M, Hirato J, Wataya T, Ahsan S, Tateishi K, Yamamoto T, Rodrigues FJ, Takahashi H, Hovestadt V, Suva ML, Taylor MD, Eberhart CG, Fujii Y, Kakita A (2021) Gli3 induces neuronal differentiation in SHH-activated and WNT-activated medulloblastoma. J Neuropathol Exp Neurol 80 (2): 129-136

2.

Tanji K, Mori F, Shirai F, Fukami T, Seimiya H, Utsumi J, Kakita A, Wakabayashi K (2021) Novel tankyrase inhibitors suppress TDP-43 aggregate formation. Biochem Biophys Res Commun 537: 85-92

1.

Sugimoto K, Ichikawa-Tomikawa N, Nishiura K, Sano Y, Kakita A, Kanda T, Chiba H (2021) Serotonin/5-HT1A signaling in the neurovascular unit regulates endothelial CLDN5 expression. Int J Mol Sci 22 (1): E254